DAO 127:225-230 (2018)  -  DOI: https://doi.org/10.3354/dao03204

NOTE
Multicentric plasmacytoma in a harbor porpoise Phocoena phocoena off the coast of Whidbey Island, Washington State, USA

Barry H. Rickman1,2,3,*, Tim Morgan4, Matthew Klope2, Susan Berta2, Sandra Dubpernell2, Howard Garrett2, Mary Jo Adams2, Stephanie A. Norman2,5

1Faculty of Veterinary Science, University of Sydney, Camden, New South Wales 2570, Australia
2Central Puget Sound Marine Mammal Stranding Network, Whidbey Island, Washington 98249, USA
3Sound VetPath, Edmonds, Washington 98020, USA
4Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi 39762, USA
5Marine-Med: Marine Research, Epidemiology, and Veterinary Medicine, Bothell, Washington 98021, USA
*Corresponding author:

ABSTRACT: Necropsy of a female adult pregnant harbor porpoise Phocoena phocoena revealed a multicentric plasmacytoma. The plasmacytoma infiltrated the cranial lung lobes, mediastinal lymph nodes and the spleen. Diagnosis was based on gross, histopathologic and immunohistochemical studies. Histopathology revealed a diffuse proliferation of atypical pleomorphic neoplastic round cells with plasmacytic features. Positive immunohistochemistry with anti-CD79a and anti-CD20 antibody markers and anti-multiple myeloma oncogene 1 (MUM-1) for plasmacytoma confirmed this neoplasm to be of B-cell origin. This is the first recorded case of a plasmacytoma in a harbor porpoise. Routine viral screening was negative via standard PCR for herpesvirus and reverse transcriptase PCR for morbillivirus. Retroviral screening was not performed.


KEY WORDS: Cancer · Neoplasia · Cetacean · Harbor porpoise · Multicentric anaplasmic plasmacytoma · Phocoena phocoena · Marine mammal


Full text in pdf format 
Cite this article as: Rickman BH, Morgan T, Klope M, Berta S and others (2018) Multicentric plasmacytoma in a harbor porpoise Phocoena phocoena off the coast of Whidbey Island, Washington State, USA. Dis Aquat Org 127:225-230. https://doi.org/10.3354/dao03204

Export citation
Mail this link - Contents Mailing Lists - RSS
- -