DAO 22:33-37 (1995)  -  doi:10.3354/dao022033

Low levels of vitamin E in plasma from Atlantic salmon Salmo salar with acute infectious pancreatic necrosis (IPN)

Taksdal T, Poppe T, Sivertsen T, Ferguson HW

Blood and pancreatic tissue from Atlantic salmon Salmo salar L. postsmolts were sampled from 5 sea water fish farms in Norway during clinical outbreaks of IPN. Formalin-fixed pancreatic tissue was examined histologically. The presence of IPN-virus (IPNV) in pancreatic lesions was demonstrated at all farms by means of immunohistochemistry. IPNV was isolated in cell cultures, both from kidney and pancreatic tissue sampled from 2 of the farms. alpha-Tocopherol in blood plasma was measured by HPLC. The levels of alpha-tocopherol in blood plasma from Atlantic salmon with acute IPN were significantly lower than in healthy fish sampled from the same cages. We conclude that vitamin E levels cannot be used to differentiate IPN from pancreas disease.


Infectious pancreatic necrosis . Atlantic salmon . Vitamin E . alpha-Tocopherol . Pancreas disease


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