DAO 67:15-23 (2005)  -  doi:10.3354/dao067015

Reactivation of koi herpesvirus infections in common carp Cyprinus carpio

S. St-Hilaire1,2,*, N. Beevers1, K. Way1, R. M. Le Deuff1, P. Martin1, C. Joiner1

1CEFAS Weymouth Laboratory, Barrack Road, The Nothe, Weymouth, Dorset DT4 8UB, UK
2Present address: Department of Biological Sciences, Idaho State University, Pocatello, Idaho 83209, USA

ABSTRACT: Two co-habitation studies with common carp were conducted to determine whether latent infections of koi herpesvirus (KHV) exist. Fish were exposed to KHV using 2 different temperature profiles, which induced low and high initial mortality. Subsequently, certain groups of fish were co-habited with naïve fish while others were not. Koi herpesvirus was reactivated in fish from 3 of the 5 experimental tanks. Reactivation of the virus occurred regardless of the initial mortality associated with the virus or whether fish were co-habited with naïve fish. The reactivation of the virus in our experiments occurred several months after the initial exposure to KHV and appeared to be temperature dependent.

KEY WORDS: Koi herpesvirus · KHV · Latent infections · Reactivation · Common carp · Co-habitation

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