DAO 79:169-172 (2008)  -  DOI: https://doi.org/10.3354/dao01893

Background pathology of the ovary in a laboratory population of zebrafish Danio rerio

Stefanie Rossteuscher1, Heike Schmidt-Posthaus1, Christoph Schäfers2, Matthias Teigeler2, Helmut Segner1,*

1Centre for Fish and Wildlife Health, University of Bern, PO Box 8466, 3001 Bern, Switzerland
2Fraunhofer Institute for Molecular Biology and Applied Ecology IME, 57392 Schmallenberg, Germany
*Corresponding author. Email:

ABSTRACT: Adult zebrafish Danio rerio originating from one stock used as control animals in a toxicological study were examined histopathologically for the occurrence of spontaneous lesions in the gonads. While no histopathological changes were seen in the testes, the ovaries showed lesions consisting mainly of acute granulomatous inflammation with increased atresia and the presence of egg debris in the ovarian parenchyma and in the oviduct. Since infectious agents could not be detected and the fish were not exposed to toxicants, we consider these lesions as spontaneous alterations of the ovaries.


KEY WORDS: Zebrafish · Gonad · Histopathology


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Cite this article as: Rossteuscher S, Schmidt-Posthaus H, Schäfers C, Teigeler M, Segner H (2008) Background pathology of the ovary in a laboratory population of zebrafish Danio rerio. Dis Aquat Org 79:169-172. https://doi.org/10.3354/dao01893

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