DAO 92:83-88 (2010) - DOI: https://doi.org/10.3354/dao02273
NOTE
Seminoma in a koi carp Cyprinus carpio: histopathological and immunohistochemical findings
Rubina Sirri1,*, Luciana Mandrioli1, Valeria Grieco2, Barbara Bacci1, Barbara Brunetti1, Giuseppe Sarli1, Heike Schmidt-Posthaus3
ABSTRACT: A spontaneous seminoma in a 3 yr old male koi carp Cyprinus carpio L. is described. The animal, presenting a symmetric abdominal enlargement, showed a celomatic multinodular, white-yellowish and firm mass that infiltrated the liver and the intestine wall. Histologically, the neoplasm was non-encapsulated and poorly demarcated, showed invasive growth and was characterized by a lobular architecture, subdivided by abundant fibro-connective septa. Large necrotic and calcified areas together with small aggregates of residual spermatids were present. We diagnosed a classical seminoma with a diffuse pattern. Neoplastic cells cross-reacted with vimentin, placental alkaline phosphatase, and c-KIT. An immunohistochemical phenotypization of the tumor was performed to exclude other celomatic neoplasms and to compare this seminoma with those reported in mammals and humans.
KEY WORDS: Seminoma · Koi carp · Histology · Immunohistochemistry
| Full text in pdf format | Cite this article as: Sirri R, Mandrioli L, Grieco V, Bacci B, Brunetti B, Sarli G, Schmidt-Posthaus H
(2010) Seminoma in a koi carp Cyprinus carpio: histopathological and immunohistochemical findings. Dis Aquat Org 92:83-88. https://doi.org/10.3354/dao02273
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