DAO 107:113-120 (2013) - DOI: https://doi.org/10.3354/dao02666
Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus
Marc Y. Engelsma1, Keith Way2, Melanie J. Dodge2, Michal Voorbergen-Laarman1, Valentina Panzarin3, Miriam Abbadi3, Mansour El-Matbouli4, Helle Frank Skall5, Søren Kahns5,6, David M. Stone2,*
*Corresponding author. Email: david.stone@cefas.co.uk
ABSTRACT: Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a devastating virus of carp. Using generic primers for the DNA polymerase and the major capsid protein genes of cyprinid herpesviruses, nucleotide sequences divergent from previously described CyHV-3 were obtained. At least 3 novel groups of putative CyHV-3-like viruses were identified, sharing 95 to 98% nucleotide identity with CyHV-3 strains. Carp carrying the CyHV-3 variants did not show clinical signs consistent with CyHV-3 infection and originated from locations with no actual CyHV-3 outbreaks. These strains might represent low- or non-pathogenic variants of CyHV-3.
KEY WORDS: Carp · Alloherpesviridae · Phylogeny · CyHV-3 · Variant strains
| Full text in pdf format | Cite this article as: Engelsma MY, Way K, Dodge MJ, Voorberger-Laarman M and others (2013) Detection of novel strains of cyprinid herpesvirus closely related to koi herpesvirus. Dis Aquat Org 107:113-120. https://doi.org/10.3354/dao02666
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