Inter-Research > DAO > v111 > n2 > p165-171  
Diseases of Aquatic Organisms

via Mailchimp

DAO 111:165-171 (2014)  -  DOI:

First outbreak of sleeping disease in Switzerland: disease signs and virus characterization

Heike Schmidt-Posthaus1,*, Nicolas Diserens1, Monika Jankowska Hjortaas2, Ralph Knüsel3, Regula Hirschi1, Torunn Taksdal2

1Centre for Fish and Wildlife Health, Department of Infectious Disease and Pathobiology, University of Berne, Laenggassstrasse 122, PO Box 8466, 3001 Berne, Switzerland
2Norwegian Veterinary Institute, Ullevålsveien 68, PO Box 750 Sentrum, 0106 Oslo, Norway
3Fishdoc GmbH, Schaubhus, 6026 Rain, Switzerland
*Corresponding author:

ABSTRACT: Sleeping disease is a contagious disease mainly of freshwater farmed rainbow trout, caused by salmonid alphavirus (SAV) Subtype 2. Here we describe the first case in Switzerland. Pathological changes ranged from acute pancreas necrosis to more chronic lesions with complete loss of exocrine pancreas and simultaneous degenerative, inflammatory and regenerative heart and muscle lesions. The partial sequencing of SAV E2 and nsp3 genes placed the Swiss SAV variant within the Subtype 2 clustering together with freshwater isolates from UK and continental Europe. Although mortality stayed low, growth rates were significantly reduced, making the disease economically relevant.

KEY WORDS: Sleeping disease · Salmonid alphavirus · SAV · Subtype 2 · Pathology · Trout · Phylogenetic analysis

Full text in pdf format 
Cite this article as: Schmidt-Posthaus H, Diserens N, Jankowska Hjortaas M, Knüsel R, Hirschi R, Taksdal T (2014) First outbreak of sleeping disease in Switzerland: disease signs and virus characterization. Dis Aquat Org 111:165-171.

Export citation
Mail this link - Contents Mailing Lists - RSS
Facebook - - linkedIn