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Diseases of Aquatic Organisms

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DAO 121:201-209 (2016)  -  DOI:

Praziquantel delivery via moist pellets to treat monogenean parasites of yellowtail kingfish Seriola lalandi: efficacy and feed acceptance

James M. Forwood1,*, Erin J. Bubner1, Matt Landos2, Marty R. Deveney3,4, Trent D’Antignana1

1School of Biological Sciences, Lincoln Marine Science Centre, Flinders University, Port Lincoln, SA 5606, Australia
2Future Fisheries Veterinary Services Pty Ltd, East Ballina, NSW 2478, Australia
3South Australian Research and Development Institute (SARDI), and 4Marine Innovation Southern Australia (MISA), West Beach, SA 5024, Australia
*Corresponding author:

ABSTRACT: Praziquantel (PZQ) is registered for oral use against Benedenia seriolae infecting Seriola spp. in Japan, but its bitter taste causes poor palatability. Incorporating PZQ in a moist pellet may help mask the flavor to improve intake. Altering delivery, however, may influence efficacy. We assessed the minimum effective concentrations of PZQ in moist pellets delivered by intubation for the monogeneans Zeuxapta seriolae and B. seriolae infecting yellowtail kingfish Seriola lalandi in flow-through tanks. The optimised dose was then evaluated in a sea-cage of S. lalandi to assess feed acceptance and efficacy. During intubation trials, efficacy was assessed as a percent reduction compared to control groups; in the field trial, efficacy was assessed by a percent reduction after treatment. PZQ delivered by intubation at 70 mg kg-1 body weight (BW) for 3 d was 99.7 and 81.7% effective against Z. seriolae and B. seriolae, respectively. Increasing the dose to 120 mg kg-1 BW for 3 d had a similar efficacy against Z. seriolae (98.4%) and increased efficacy against B. seriolae to 89.2%, but partial emesis of the medicated feed was sometimes noted. S. lalandi in a sea-cage at 17°C readily consumed PZQ administered daily in moist pellets at 70 mg kg-1 BW for 3 d (inclusion rate: 5.15 g kg-1), which significantly reduced Z. seriolae and B. seriolae abundance with 99.4 and 81.6% efficacy, respectively. Juvenile B. seriolae were common on the eyes of fish post-treatment which indicates a strategically timed repeat treatment is necessary.

KEY WORDS: Abundance · Intubation · Oral · Zeuxapta seriolae · Benedenia seriolae

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Cite this article as: Forwood JM, Bubner EJ, Landos M, Deveney MR, D’Antignana T (2016) Praziquantel delivery via moist pellets to treat monogenean parasites of yellowtail kingfish Seriola lalandi: efficacy and feed acceptance. Dis Aquat Org 121:201-209.

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