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Diseases of Aquatic Organisms

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DAO 23:109-114 (1995)  -  doi:10.3354/dao023109

Immunological evidence for the presence of an IgM-like immunoglobulin in the eggs of coho salmon Oncorhynchus kisutch

Yousif AN, Albright LJ, Evelyn TPT

Western blot analysis of the yolk extract of coho salmon eggs revealed the presence of an immunoglobulin-like protein molecule that reacted with antibodies specific for coho serum immunoglobulin (IgM). Sucrose gradient ultracentrifugation analysis of the yolk extract showed that the molecule 'sedimented' in a manner similar to bovine serum immunoglobulin IgG. This indicates that coho salmon eggs contain a low molecular weight form of serum IgM, perhaps a breakdown product, or a precursor of IgM. The precise function of the reported intra-ovum IgM-like protein is unknown.

IgM . Immunoglobulin . Salmonids . Eggs

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