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Diseases of Aquatic Organisms

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DAO 41:1-8 (2000)  -  doi:10.3354/dao041001

Genetic analysis of infectious salmon anaemia virus (ISAV) from Scotland

C. O. Cunningham*, M. Snow

Fisheries Research Services (FRS) Marine Laboratory, PO Box 101, Victoria Road, Aberdeen AB11 9DB, Scotland, UK

ABSTRACT: The nucleotide sequences of segments 2 and 8 of infectious salmon anaemia virus (ISAV) isolates from Scotland were determined. These were used to predict amino acid sequences of the products of these segments. The sequences were compared with those previously published for ISAV from Norway and North America. Nucleotide and amino acid variations were found in the Scottish isolate, indicating that it is not identical to those Norwegian or North American strains. Although phylogenetic analysis of the sequences was not possible, it was clear that the Scottish isolate is more closely related to the Norwegian strain than the North American. Sequencing further isolates that are geographically or temporally separated will be important in advancing understanding of the epidemiology of this important disease.

KEY WORDS: Infectious salmon anaemia virus (ISAV) · Atlantic salmon Salmo salar · Nucleotide sequence

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