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Diseases of Aquatic Organisms

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DAO 51:81-83 (2002)  -  doi:10.3354/dao051081

Inhibition of hemolytic activity of Aeromonas salmonicida GCAT in rainbow trout red blood cells by a monoclonal antibody

Ingolf Lachmann*, Karl Droessler

Institute for Zoology, University of Leipzig, Talstrasse 33, 04103 Leipzig, Germany

ABSTRACT: The present study shows that a monoclonal antibody (MAb) directed to Aeromonas salmonicida glycerophospholipid:cholesterol acyltransferase (GCAT) is capable of protecting rainbow trout red blood cells from the cytotoxic effects of the enzyme in vitro.

KEY WORDS: Aeromonas salmonicida · GCAT · Monoclonal antibody

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