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Diseases of Aquatic Organisms

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DAO 92:83-88 (2010)  -  DOI:

Seminoma in a koi carp Cyprinus carpio: histopathological and immunohistochemical findings

Rubina Sirri1,*, Luciana Mandrioli1, Valeria Grieco2, Barbara Bacci1, Barbara Brunetti1, Giuseppe Sarli1, Heike Schmidt-Posthaus3

1Servizio di Prova di Anatomia Patologica, Dipartimento di Sanità Pubblica Veterinaria e Patologia Animale, Facoltà di Medicina Veterinaria, Alma Mater Studiorum Università di Bologna, Via Tolara di Sopra 50, 40064 Ozzano Emilia (BO), Italy
2Dipartimento di Patologia Animale, Igiene e Sanità Pubblica Veterinaria, Sezione di Anatomia Patologica Veterinaria e Patologia Aviare, Facoltà di Medicina Veterinaria, Università degli Studi di Milano, Via Celoria 10, 20133 Milan, Italy
3Centre for Fish and Wildlife Health, Institute of Animal Pathology, University of Bern, Laenggassstrasse 122, 3012 Bern, Switzerland

ABSTRACT: A spontaneous seminoma in a 3 yr old male koi carp Cyprinus carpio L. is described. The animal, presenting a symmetric abdominal enlargement, showed a celomatic multinodular, white-yellowish and firm mass that infiltrated the liver and the intestine wall. Histologically, the neoplasm was non-encapsulated and poorly demarcated, showed invasive growth and was characterized by a lobular architecture, subdivided by abundant fibro-connective septa. Large necrotic and calcified areas together with small aggregates of residual spermatids were present. We diagnosed a classical seminoma with a diffuse pattern. Neoplastic cells cross-reacted with vimentin, placental alkaline phosphatase, and c-KIT. An immunohistochemical phenotypization of the tumor was performed to exclude other celomatic neoplasms and to compare this seminoma with those reported in mammals and humans.

KEY WORDS: Seminoma · Koi carp · Histology · Immunohistochemistry

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Cite this article as: Sirri R, Mandrioli L, Grieco V, Bacci B, Brunetti B, Sarli G, Schmidt-Posthaus H (2010) Seminoma in a koi carp Cyprinus carpio: histopathological and immunohistochemical findings. Dis Aquat Org 92:83-88.

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