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Diseases of Aquatic Organisms

    DAO prepress abstract   -  DOI: https://doi.org/10.3354/dao03418

    Persistent Mùˆllerian duct syndrome in a beluga whale Delphinapterus leucas

    Raphaela Stimmelmayr*, Tatiana Ferrer, David S. Rotstein

    *Corresponding author:

    ABSTRACT: This case-study describes a Persistent Müllerian duct syndrome (PMDS), a rare form of XY disorder of sex development (DSD), in a mature (>15 yr) beluga whale Delphinapterus leucas. The phenotypically and genetically male beluga whale had both Müllerian (paramesonephric) and Wolffian (mesonephric) duct derivatives. A mild hydrometra was present. Gross and histological analyses indicated the testes were atrophied. Histopathologic findings in the testes also included fibrosis in addition to ductus deferens ductular dilation, epididymal ductular dilation, lymphoplasmacytic balanitis, uterine glandular atrophy, and endometrial fibrosis. DSDs are rarely reported in cetaceans and to date, Persistent Müllerian duct syndrome has not previously been described in a cetacean.