DAO 122:73-76 (2016)  -  DOI: https://doi.org/10.3354/dao03065

NOTE
Squamous cell carcinoma in a wild European bullhead Cottus gobio 

F. Quaglio1, V. Zappulli1, L. Poppi1, P. Capovilla2, F. Capparucci3, F. Marino3,*

1Dept. of Comparative Biomedicine and Food Science, University of Padua, 35020 Padua, Italy
2ULSS1 Belluno via Feltre, 32100 Belluno, Italy
3Dept. of Chemical, Pharmaceutical, Biological and Environmental Sciences, University of Messina, 98166 Messina, Italy
*Corresponding author:

ABSTRACT: A pharyngeal tumor was found in a wild European bullhead. The tumor mass appeared underneath the operculum and was bilobed. The major neoplastic component showed diffuse epithelial squamous differentiation. Crossmonn’s trichrome allowed identification of connective tissues whereas no neoplastic cells were stained. Periodic acid-Schiff was negative within the mass, and Giemsa did not show any further diagnostic significance. Immunohistochemistry showed diffuse positive cytoplasmic staining of the neoplastic population with an anti-human pancytokeratin antibody. Vimentin was negative and exclusively stained the stroma. On the basis of the morphological and immunohistochemical results, a squamous cell carcinoma was diagnosed.


KEY WORDS: Carcinoma · Pharynx · Cottus gobio · Immunohistochemistry


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Cite this article as: Quaglio F, Zappulli V, Poppi L, Capovilla P, Capparucci F, Marino F (2016) Squamous cell carcinoma in a wild European bullhead Cottus gobio . Dis Aquat Org 122:73-76. https://doi.org/10.3354/dao03065

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