DAO 21:1-5 (1995)  -  doi:10.3354/dao021001

Demonstration of a protective immune response in infectious salmon anaemia (ISA)-infected Atlantic salmon Salmo salar

Falk K, Dannevig BH

ABSTRACT: A protective immune response in infectious salmon anaemia (ISA)-infected Atlantic salmon Salmo salar L. was demonstrated. Atlantic salmon that had survived an ISA infection 75 d previously were less susceptible to reinfection. Fish passively immunized with serum from fish that had recovered from ISA were found to be partly protected against ISA. Neutralizing activity of ISA-convalescent antiserum was demonstrated by mixing convalescent antiserum with ISA-infective tissue homogenate and injecting this preparation into Atlantic salmon.


KEY WORDS: Infectious salmon anaemia . Atlantic salmon . Immune response . Neutralizing antibody . Passive immunity


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